一对经历丰富的警察搭档争分夺秒地从过去和假线索中寻找蛛丝马迹，以抓获一个以小女孩为犯罪对象的神秘连环杀手。 一名負債累累的男子勉強同意騎車載一名美國遊客遊覽印度各地，兩人的南轅北轍導致口角不斷，卻也意外培養出感情。 AreallifeaccountofthedeadlyNipahvirusoutbreakinKerala,andthecourageousfightputonbyseveralindividualswhichhelpedtocontaintheepidemic ThallumaalarevolvesaroundaseriesoffightsinthelifeofayoungmannamedWazim,Amongthesefights,theonethatendsuptoppingthelististhemassivefightthatbreaksoutonhisweddingday,whichtransformsWazimintoManavalanWazim,theinternetsensationheistoday.ThefactthathisbridewasBeepaathu,anevenbiggerinternetcelebrity,onlymakesthingsworse.ThePoliceS.I,RegiMathew,whonowbelieveshisonlyshotatredemptionandgoingbacktonormalisthroughafistfighttotheendwithWazim.Asbothmengearupforthefinalbrawl,Wazimmustalsofightthefightofwinningbacktheheartofhislostloveandoncebride,Beepaathu. 
